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New insights into the evolutionary origins of the RAG proteins and V(D)J recombination

The adaptive immune system of jawed vertebrates relies on V(D)J recombination as one of the main processes to generate the diverse array of receptors necessary for the recognition of a wide range of pathogens. The DNA cleavage reaction necessary for the assembly of the antigen receptor genes from an...

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Bibliografiske detaljer
Udgivet i:FEBS J
Main Authors: Carmona, Lina Marcela, Schatz, David G.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459667/
https://ncbi.nlm.nih.gov/pubmed/27973733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13990
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