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The origins of the RAG genes – from transposition to V(D)J recombination
The Recombination Activating Genes 1 and 2 (Rag1 and Rag2) encode the key enzyme that is required for the generation of the highly diversified antigen receptor repertoire central to adaptive immunity. The longstanding model proposed that this gene pair was acquired by horizontal gene transfer to exp...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823946/ https://ncbi.nlm.nih.gov/pubmed/20004590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2009.11.004 |
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