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Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination
Co-option of RAG1 and RAG2 for antigen receptor gene assembly by V(D)J recombination was a crucial event in the evolution of jawed vertebrate adaptive immunity. RAG1/2 are proposed to have arisen from a transposable element, but definitive evidence for this is lacking. Here we report the discovery o...
Gorde:
| Argitaratua izan da: | Cell |
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| Egile Nagusiak: | , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017859/ https://ncbi.nlm.nih.gov/pubmed/27293192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.032 |
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