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Transposon Molecular Domestication and the Evolution of the RAG Recombinase
Domestication of a transposon to give rise to the RAG1/RAG2 recombinase and V(D)J recombination was a pivotal event in the evolution of the jawed vertebrate adaptive immune system. The evolutionary adaptations that transformed the ancestral RAG transposase into a RAG recombinase with appropriately r...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494689/ https://ncbi.nlm.nih.gov/pubmed/30971819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1093-7 |
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