Transposon Molecular Domestication and the Evolution of the RAG Recombinase

Domestication of a transposon to give rise to the RAG1/RAG2 recombinase and V(D)J recombination was a pivotal event in the evolution of the jawed vertebrate adaptive immune system. The evolutionary adaptations that transformed the ancestral RAG transposase into a RAG recombinase with appropriately r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Zhang, Yuhang, Cheng, Tat Cheung, Huang, Guangrui, Lu, Qingyi, Surleac, Marius D., Mandell, Jeffrey D., Pontarotti, Pierre, Petrescu, Andrei J., Xu, Anlong, Xiong, Yong, Schatz, David G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494689/
https://ncbi.nlm.nih.gov/pubmed/30971819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1093-7
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg