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Mapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2
The RAG endonuclease consists of RAG1, which contains the active site for DNA cleavage, and RAG2, an accessory factor whose interaction with RAG1 is critical for catalytic function. How RAG2 activates RAG1 is not understood. Here, we used biolayer interferometry and pulldown assays to identify regio...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4424321/ https://ncbi.nlm.nih.gov/pubmed/25745109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638627 |
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