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Mapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2

The RAG endonuclease consists of RAG1, which contains the active site for DNA cleavage, and RAG2, an accessory factor whose interaction with RAG1 is critical for catalytic function. How RAG2 activates RAG1 is not understood. Here, we used biolayer interferometry and pulldown assays to identify regio...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Yu-Hang, Shetty, Keerthi, Surleac, Marius D., Petrescu, Andrei J., Schatz, David G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424321/
https://ncbi.nlm.nih.gov/pubmed/25745109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638627
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