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Mapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2

The RAG endonuclease consists of RAG1, which contains the active site for DNA cleavage, and RAG2, an accessory factor whose interaction with RAG1 is critical for catalytic function. How RAG2 activates RAG1 is not understood. Here, we used biolayer interferometry and pulldown assays to identify regio...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Zhang, Yu-Hang, Shetty, Keerthi, Surleac, Marius D., Petrescu, Andrei J., Schatz, David G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424321/
https://ncbi.nlm.nih.gov/pubmed/25745109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638627
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