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Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin
BACKGROUND: V(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved from a RAGL (RAG-like) transposon containing convergently-oriented RAG1-like (RAG1L) and RAG2-like (RAG2L) gene...
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| 出版年: | Mob DNA |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7204232/ https://ncbi.nlm.nih.gov/pubmed/32399063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-020-00214-y |
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