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An ancient evolutionary origin of the Rag1/2 gene locus
The diversity of antigen receptors in the adaptive immune system of jawed vertebrates is generated by a unique process of somatic gene rearrangement known as V(D)J recombination. The Rag1 and Rag2 proteins are the key mediators of this process. They are encoded by a compact gene cluster that has exc...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450146/ https://ncbi.nlm.nih.gov/pubmed/16505374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509720103 |
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