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Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination

The recombination-activating gene 1 (RAG1) and RAG2 proteins initiate V(D)J recombination, the process that assembles the B- and T-lymphocyte antigen receptor genes of jawed vertebrates. RAG1 and RAG2 are thought to have arisen from a transposable element, but the origins of this element are not und...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Carmona, Lina Marcela, Fugmann, Sebastian D., Schatz, David G.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840297/
https://ncbi.nlm.nih.gov/pubmed/27056670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278432.116
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