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RAG: A recombinase diversified

During B and T cell development, the lymphoid-specific proteins RAG1 and RAG2 act together to initiate antigen receptor gene assembly via a series of site-specific, somatic DNA rearrangements that are collectively termed V(D)J recombination. In the past 20 years, a great deal has been learned about...

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Bibliographic Details
Main Authors: Matthews, Adam G.W., Oettinger, Marjorie A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773180/
https://ncbi.nlm.nih.gov/pubmed/19621044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1776
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