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Ordered DNA release and target capture in RAG transposition
Following V(D)J cleavage, the newly liberated DNA signal ends can be either fused together into a signal joint or used as donor DNA in RAG-mediated transposition. We find that both V(D)J cleavage and release of flanking coding DNA occur before the target capture step of transposition can proceed; no...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC380985/ https://ncbi.nlm.nih.gov/pubmed/14988730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600131 |
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