Loading...

Ordered DNA release and target capture in RAG transposition

Following V(D)J cleavage, the newly liberated DNA signal ends can be either fused together into a signal joint or used as donor DNA in RAG-mediated transposition. We find that both V(D)J cleavage and release of flanking coding DNA occur before the target capture step of transposition can proceed; no...

Full description

Saved in:
Bibliographic Details
Published in:EMBO J
Main Authors: Matthews, Adam GW, Elkin, Sheryl K, Oettinger, Marjorie A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC380985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14988730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600131
Tags: Add Tag
No Tags, Be the first to tag this record!