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Ordered DNA release and target capture in RAG transposition

Following V(D)J cleavage, the newly liberated DNA signal ends can be either fused together into a signal joint or used as donor DNA in RAG-mediated transposition. We find that both V(D)J cleavage and release of flanking coding DNA occur before the target capture step of transposition can proceed; no...

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Autors principals: Matthews, Adam GW, Elkin, Sheryl K, Oettinger, Marjorie A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC380985/
https://ncbi.nlm.nih.gov/pubmed/14988730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600131
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