p53 Down-Regulates CHK1 through p21 and the Retinoblastoma Protein

Both fission yeast and mammalian cells require the function of the checkpoint kinase CHK1 for G(2) arrest after DNA damage. The tumor suppressor p53, a well-studied stress response factor, has also been shown to play a role in DNA damage G(2) arrest, although in a manner that is probably independent...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Gottifredi, Vanesa, Karni-Schmidt, Orit, Shieh, Sheau-Yann, Prives, Carol
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2001
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99561/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.4.1066-1076.2001
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