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Replication of damaged DNA in vitro is blocked by p53

The tumor suppressor protein p53 may have other roles and functions in addition to its well-documented ability to serve as a sequence-specific transcriptional activator in response to DNA damage. We showed previously that p53 can block the replication of polyomavirus origin-containing DNA (Py ori-DN...

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Detalhes bibliográficos
Main Authors: Zhou, Jianmin, Prives, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165982/
https://ncbi.nlm.nih.gov/pubmed/12853603
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