A role for ATR in the DNA damage-induced phosphorylation of p53

Phosphorylation at Ser-15 may be a critical event in the up-regulation and functional activation of p53 during cellular stress. In this report we provide evidence that the ATM–Rad3-related protein ATR regulates phosphorylation of Ser-15 in DNA-damaged cells. Overexpression of catalytically inactive...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tibbetts, Randal S., Brumbaugh, Kathryn M., Williams, Josie M., Sarkaria, Jann N., Cliby, William A., Shieh, Sheau-Yann, Taya, Yoichi, Prives, Carol, Abraham, Robert T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 1999
Gaiak:
Research Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC316393/
https://ncbi.nlm.nih.gov/pubmed/9925639
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak