Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
Chk2/hcds1, the human homolog of the Saccharomyces cerevisiae RAD53/SPK1 and Schizosaccharomyces pombe cds1 DNA damage checkpoint genes, encodes a protein kinase that is post-translationally modified after DNA damage. Like its yeast homologs, the Chk2/hCds1 protein phosphorylates Cdc25C in vitro, su...
Sábháilte in:
| Foilsithe in: | Genes Dev |
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| Príomhchruthaitheoirí: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Cold Spring Harbor Laboratory Press
2000
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10673500/ |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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