Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

Chk2/hcds1, the human homolog of the Saccharomyces cerevisiae RAD53/SPK1 and Schizosaccharomyces pombe cds1 DNA damage checkpoint genes, encodes a protein kinase that is post-translationally modified after DNA damage. Like its yeast homologs, the Chk2/hCds1 protein phosphorylates Cdc25C in vitro, su...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chehab, Nabil H., Malikzay, Asra, Appel, Michael, Halazonetis, Thanos D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2000
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316357/
https://ncbi.nlm.nih.gov/pubmed/10673500
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky