Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
Chk2/hcds1, the human homolog of the Saccharomyces cerevisiae RAD53/SPK1 and Schizosaccharomyces pombe cds1 DNA damage checkpoint genes, encodes a protein kinase that is post-translationally modified after DNA damage. Like its yeast homologs, the Chk2/hCds1 protein phosphorylates Cdc25C in vitro, su...
Enregistré dans:
| Publié dans: | Genes Dev |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2000
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10673500/ |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|