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A General Method for Selection of α-Acetolactate Decarboxylase-Deficient Lactococcus lactis Mutants To Improve Diacetyl Formation

The enzyme acetolactate decarboxylase (Ald) plays a key role in the regulation of the α-acetolactate pool in both pyruvate catabolism and the biosynthesis of the branched-chain amino acids, isoleucine, leucine, and valine (ILV). This dual role of Ald, due to allosteric activation by leucine, was use...

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Bibliografische Detailangaben
Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Curic, Mirjana, Stuer-Lauridsen, Birgitte, Renault, Pierre, Nilsson, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC91165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.65.3.1202-1206.1999
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