Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination

Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Kale, Sam B., Landree, Mark A., Roth, David B.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.459-466.2001
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