Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination

Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Kale, Sam B., Landree, Mark A., Roth, David B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.459-466.2001
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!