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Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination
Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86598/ https://ncbi.nlm.nih.gov/pubmed/11134334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.459-466.2001 |
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