Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination

Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Kale, Sam B., Landree, Mark A., Roth, David B.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2001
Aiheet:	DNA Dynamics and Chromosome Structure
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.459-466.2001
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