Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination

Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kale, Sam B., Landree, Mark A., Roth, David B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.459-466.2001
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