Conditional RAG-1 Mutants Block the Hairpin Formation Step of V(D)J Recombination

Hairpin formation serves an important regulatory role in V(D)J recombination because it requires synapsis of an appropriate pair of recombination sites. How hairpin formation is regulated and which regions of the RAG proteins perform this step remain unknown. We analyzed two conditional RAG-1 mutant...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Kale, Sam B., Landree, Mark A., Roth, David B.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2001
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.459-466.2001
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