The c-Myc Transactivation Domain Is a Direct Modulator of Apoptotic versus Proliferative Signals
We have assayed the oncogenic, proliferative, and apoptotic activities of the frequent mutations that occur in the c-myc gene in Burkitt's lymphomas. Some alleles have a modest (50 to 60%) increase in transforming activity; however, the most frequent Burkitt's lymphoma allele (T58I) had an unexpecte...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Cell Biol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2000
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4309-4319.2000 |
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