The c-Myc Transactivation Domain Is a Direct Modulator of Apoptotic versus Proliferative Signals

We have assayed the oncogenic, proliferative, and apoptotic activities of the frequent mutations that occur in the c-myc gene in Burkitt's lymphomas. Some alleles have a modest (50 to 60%) increase in transforming activity; however, the most frequent Burkitt's lymphoma allele (T58I) had an unexpecte...

Descripció completa

Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Chang, David W., Claassen, Gisela F., Hann, Stephen R., Cole, Michael D.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2000
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4309-4319.2000
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!