c-Myc Is Necessary for DNA Damage-Induced Apoptosis in the G(2) Phase of the Cell Cycle

The c-myc proto-oncogene encodes a transcription factor that participates in the regulation of cellular proliferation, differentiation, and apoptosis. Ectopic overexpression of c-Myc has been shown to sensitize cells to apoptosis. We report here that cells lacking c-Myc activity due to disruption of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Adachi, Susumu, Obaya, Alvaro J., Han, Zhiyong, Ramos-Desimone, Noemi, Wyche, James H., Sedivy, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87219/
https://ncbi.nlm.nih.gov/pubmed/11438650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4929-4937.2001
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge