c-Myc Is Necessary for DNA Damage-Induced Apoptosis in the G(2) Phase of the Cell Cycle

The c-myc proto-oncogene encodes a transcription factor that participates in the regulation of cellular proliferation, differentiation, and apoptosis. Ectopic overexpression of c-Myc has been shown to sensitize cells to apoptosis. We report here that cells lacking c-Myc activity due to disruption of...

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Bibliografiske detaljer
Main Authors: Adachi, Susumu, Obaya, Alvaro J., Han, Zhiyong, Ramos-Desimone, Noemi, Wyche, James H., Sedivy, John M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87219/
https://ncbi.nlm.nih.gov/pubmed/11438650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4929-4937.2001
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