c-Myc Is Necessary for DNA Damage-Induced Apoptosis in the G(2) Phase of the Cell Cycle

The c-myc proto-oncogene encodes a transcription factor that participates in the regulation of cellular proliferation, differentiation, and apoptosis. Ectopic overexpression of c-Myc has been shown to sensitize cells to apoptosis. We report here that cells lacking c-Myc activity due to disruption of...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Adachi, Susumu, Obaya, Alvaro J., Han, Zhiyong, Ramos-Desimone, Noemi, Wyche, James H., Sedivy, John M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.15.4929-4937.2001
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