Identification of CDK4 as a target of c-MYC

The prototypic oncogene c-MYC encodes a transcription factor that can drive proliferation by promoting cell-cycle reentry. However, the mechanisms through which c-MYC achieves these effects have been unclear. Using serial analysis of gene expression, we have identified the cyclin-dependent kinase 4...

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Detalhes bibliográficos
Main Authors: Hermeking, Heiko, Rago, Carlo, Schuhmacher, Marino, Li, Qing, Barrett, John F., Obaya, Alvaro J., O'Connell, Brenda C., Mateyak, Maria K., Tam, Wanny, Kohlhuber, Franz, Dang, Chi V., Sedivy, John M., Eick, Dirk, Vogelstein, Bert, Kinzler, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15783/
https://ncbi.nlm.nih.gov/pubmed/10688915
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