Identification of CDK4 as a target of c-MYC

The prototypic oncogene c-MYC encodes a transcription factor that can drive proliferation by promoting cell-cycle reentry. However, the mechanisms through which c-MYC achieves these effects have been unclear. Using serial analysis of gene expression, we have identified the cyclin-dependent kinase 4...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Hermeking, Heiko, Rago, Carlo, Schuhmacher, Marino, Li, Qing, Barrett, John F., Obaya, Alvaro J., O'Connell, Brenda C., Mateyak, Maria K., Tam, Wanny, Kohlhuber, Franz, Dang, Chi V., Sedivy, John M., Eick, Dirk, Vogelstein, Bert, Kinzler, Kenneth W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2000
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050586197
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