The c-Myc Transactivation Domain Is a Direct Modulator of Apoptotic versus Proliferative Signals

We have assayed the oncogenic, proliferative, and apoptotic activities of the frequent mutations that occur in the c-myc gene in Burkitt's lymphomas. Some alleles have a modest (50 to 60%) increase in transforming activity; however, the most frequent Burkitt's lymphoma allele (T58I) had an unexpecte...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Chang, David W., Claassen, Gisela F., Hann, Stephen R., Cole, Michael D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10825194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.12.4309-4319.2000
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