c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets

We report here that the expression of virtually all proposed c-Myc target genes is unchanged in cells containing a homozygous null deletion of c-myc. Two noteworthy exceptions are the gene cad, which has reduced log phase expression and serum induction in c-myc null cells, and the growth arrest gene...

Full description

Saved in:
Bibliographic Details
Published in:Genes Dev
Main Authors: Bush, Andrew, Mateyak, Maria, Dugan, Kerri, Obaya, Alvaro, Adachi, Susumu, Sedivy, John, Cole, Michael
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.24.3797
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items