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A role for transcriptional repression of p21(CIP1) by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest

c-Myc plays a vital role in cell-cycle progression. Deregulated expression of c-Myc can overcome cell-cycle arrest in order to promote cellular proliferation. Transforming growth factor β (TGFβ) treatment of immortalized human keratinocyte cells inhibits cell-cycle progression and is characterized b...

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Detalhes bibliográficos
Main Authors: Claassen, Gisela F., Hann, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16893/
https://ncbi.nlm.nih.gov/pubmed/10920185
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