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Distinct states of proinsulin misfolding in MIDY
A precondition for efficient proinsulin export from the endoplasmic reticulum (ER) is that proinsulin meets ER quality control folding requirements, including formation of the Cys(B19)–Cys(A20) “interchain” disulfide bond, facilitating formation of the Cys(B7)–Cys(A7) bridge. The third proinsulin di...
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| 出版年: | Cell Mol Life Sci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8316239/ https://ncbi.nlm.nih.gov/pubmed/34245311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03871-1 |
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