A carregar...
Cells deploy a two-pronged strategy to rectify misfolded proinsulin aggregates
Insulin gene coding sequence mutations are known to cause Mutant INS-gene-induced Diabetes of Youth (MIDY), yet the cellular pathways needed to prevent misfolded proinsulin accumulation remain incompletely understood. Here we report that Akita mutant proinsulin forms detergent-insoluble aggregates t...
Na minha lista:
| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688957/ https://ncbi.nlm.nih.gov/pubmed/31176671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.011 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|