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The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice.

Saliva, while often taken for granted, is indispensable for oral health and overall well-being, as inferred from the significant impairments suffered by patients with salivary gland dysfunction. Here, we show that treatment with several structurally-distinct PAN-PDE4 inhibitors, but not a PDE3 inhib...

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Bibliografische gegevens
Gepubliceerd in:Biochem J
Hoofdauteurs: Boyd, Abigail, Aragon, Ileana V., Saleh, Lina Abou, Southers, Dylan, Richter, Wito
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218889/
https://ncbi.nlm.nih.gov/pubmed/33944911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210212
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