Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker

Ribonucleotides (rNTPs) are predicted to be incorporated into the genome at a rate of up to 3 million times per cell division, making rNTPs the most common non-standard nucleotide in the human genome. Typically, misinserted ribonucleotides are repaired by the ribonucleotide excision repair (RER) pat...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Hoitsma, Nicole M., Click, Timothy H., Agarwal, Pratul K., Freudenthal, Bret D.
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207216/
https://ncbi.nlm.nih.gov/pubmed/34188778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.035
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