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Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase β
During oxidative stress, inflammation, or environmental exposure, ribo- and deoxyribonucleotides are oxidatively modified. 8-Oxo-7,8-dihydro-2′-guanosine (8-oxo-G) is a common oxidized nucleobase whose deoxyribonucleotide form, 8-oxo-dGTP, has been widely studied and demonstrated to be a mutagenic s...
Tallennettuna:
| Julkaisussa: | J Biol Chem |
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| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7008369/ https://ncbi.nlm.nih.gov/pubmed/31892517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011569 |
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