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Mechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase β

DNA polymerases play vital roles in the maintenance and replication of genomic DNA by synthesizing new nucleotide polymers using nucleoside triphosphates as substrates. Deoxynucleoside triphosphates (dNTPs) are the canonical substrates for DNA polymerases; however, some bacterial polymerases have be...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Varela, Fausto A., Freudenthal, Bret D.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277322/
https://ncbi.nlm.nih.gov/pubmed/33475337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00847
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