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History of DNA polymerase β X-ray crystallography

DNA polymerase β (Pol β) is an essential mammalian enzyme involved in the repair of DNA damage during the base excision repair (BER) pathway. In hopes of faithfully restoring the coding potential to damaged DNA during BER, Pol β first uses a lyase activity to remove the 5′-deoxyribose phosphate moie...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Whitaker, Amy M., Freudenthal, Bret D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586737/
https://ncbi.nlm.nih.gov/pubmed/33087265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102928
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