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Mechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase β

DNA polymerases play vital roles in the maintenance and replication of genomic DNA by synthesizing new nucleotide polymers using nucleoside triphosphates as substrates. Deoxynucleoside triphosphates (dNTPs) are the canonical substrates for DNA polymerases; however, some bacterial polymerases have be...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Varela, Fausto A., Freudenthal, Bret D.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277322/
https://ncbi.nlm.nih.gov/pubmed/33475337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00847
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