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Activated Ribonucleotides Undergo a Sugar Pucker Switch upon Binding to a Single-Stranded RNA Template

[Image: see text] Template-directed polymerization of chemically activated ribonucleotide monomers, such as nucleotide 5′-phosphorimidazolides, has been studied as a model for nonenzymatic RNA replication during the origin of life. Kinetic studies of the polymerization of various nucleotide monomers...

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Detalhes bibliográficos
Principais autores: Zhang, Na, Zhang, Shenglong, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448298/
https://ncbi.nlm.nih.gov/pubmed/22296305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja212027q
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