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Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding

Caspases are cysteine aspartate proteases that are major players in key cellular processes, including apoptosis and inflammation. Specifically, caspase-6 has also been implicated in playing a unique and critical role in neurodegeneration; however, structural similarities between caspase-6 and other...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Dagbay, Kevin B., Bolik-Coulon, Nicolas, Savinov, Sergey N., Hardy, Jeanne A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377803/
https://ncbi.nlm.nih.gov/pubmed/28154009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773499
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