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Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis
Caspases are cysteine–aspartic proteases involved in the regulation of programmed cell death (apoptosis) and a number of other biological processes. Despite overall similarities in structure and active-site composition, caspases show striking selectivity for particular protein substrates. Exosites a...
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| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322879/ https://ncbi.nlm.nih.gov/pubmed/30420425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005914 |
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