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Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics
Many peptidases are thought to require non-active site interaction surfaces, or exosites, to recognize and cleave physiological substrates with high specificity and catalytic efficiency. However, the existence and function of protease exosites remain obscure owing to a lack of effective methods to i...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858821/ https://ncbi.nlm.nih.gov/pubmed/22944693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0162 |
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