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Phosphorylation Regulates Assembly of the Caspase-6 Substrate-Binding Groove
Caspases, a family of apoptotic proteases, are increasingly recognized as being extensively phosphorylated, usually leading to inactivation. To date, no structural mechanism for phosphorylation-based caspase inactivation is available, although this information may be key to achieving caspase-specifi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3591518/ https://ncbi.nlm.nih.gov/pubmed/22483120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.02.003 |
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