Glutamine Inhibition Reduces Iatrogenic Laryngotracheal Stenosis

OBJECTIVE/HYPOTHESIS: Glutamine inhibition has been demonstrated an antifibrotic effect in iatrogenic laryngotracheal stenosis (iLTS) scar fibroblasts in vitro. We hypothesize that broadly active glutamine antagonist, DON will reduce collagen formation and fibrosis-associated gene expression in iLTS...

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Detaylı Bibliyografya
Yayımlandı:Laryngoscope
Asıl Yazarlar: Tsai, Hsiu-Wen, Lina, Ioan, Motz, Kevin M, Chung, Liam, Ding, Dacheng, Murphy, Michael K., Feeley, Michael, Elisseeff, Jennifer H., Hillel, Alexander T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205976/
https://ncbi.nlm.nih.gov/pubmed/33433011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.29385
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