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Glutamine Inhibition Reduces Iatrogenic Laryngotracheal Stenosis

OBJECTIVE/HYPOTHESIS: Glutamine inhibition has been demonstrated an antifibrotic effect in iatrogenic laryngotracheal stenosis (iLTS) scar fibroblasts in vitro. We hypothesize that broadly active glutamine antagonist, DON will reduce collagen formation and fibrosis-associated gene expression in iLTS...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Laryngoscope
Päätekijät: Tsai, Hsiu-Wen, Lina, Ioan, Motz, Kevin M, Chung, Liam, Ding, Dacheng, Murphy, Michael K., Feeley, Michael, Elisseeff, Jennifer H., Hillel, Alexander T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205976/
https://ncbi.nlm.nih.gov/pubmed/33433011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.29385
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