Targeting Metabolic Abnormalities to Reverse Fibrosis in Iatrogenic Laryngotracheal Stenosis

OBJECTIVE: Management of laryngotracheal stenosis (LTS) remains primarily surgical, with a critical need to identify targets for adjuvant therapy. Laryngotracheal stenosis scar fibroblasts exhibit a profibrotic phenotype with distinct metabolic shifts, including an increased glycolysis/oxidative pho...

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發表在:Laryngoscope
Main Authors: Murphy, Michael K., Motz, Kevin M, Ding, Dacheng, Yin, Linda, Duvvuri, Madhavi, Feeley, Michael, Hillel, Alexander T.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771827/
https://ncbi.nlm.nih.gov/pubmed/28940431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.26893
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