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Preliminary Preclinical Study of Chol-DsiRNA Polyplexes Formed with PLL[30]-PEG[5K] for the RNAi-Based Therapy of Breast Cancer
RNA interference molecules have tremendous potential for cancer therapy but are limited by insufficient potency after i.v. administration. We previously found that Chol-DsiRNA Polyplexes formed between cholesterol-modified dicer-substrate siRNA (Chol-DsiRNA) and the cationic diblock copolymer PLL[30...
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| Publicat a: | Nanomedicine |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184584/ https://ncbi.nlm.nih.gov/pubmed/33545405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2021.102363 |
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