The Modification of siRNA with 3′ Cholesterol to Increase Nuclease Protection and Suppression of Native mRNA by Select siRNA Polyplexes

Por Ambardekar, Vishakha V., Han, Huai-Yun, Varney, Michelle L., Vinogradov, Serguei V., Singh, Rakesh K., Vetro, Joseph A.
Publicado em 2010

The efficacy of nuclease-resistant Chol-siRNA in primary breast tumors following complexation with PLL-PEG(5K)

Por Ambardekar, Vishakha V., Wakaskar, Rajesh R., Sharma, Bhawna, Bowman, Joy, Vayaboury, Willy, Singh, Rakesh K., Vetro, Joseph A.
Publicado em 2013

Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors aft...

Por Ambardekar, Vishakha V., Wakaskar, Rajesh R., Ye, Zhen, Curran, Stephen M., McGuire, Timothy R., Coulter, Don W., Singh, Rakesh K., Vetro, Joseph A.
Publicado no Int J Pharm (2018)

Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residen...

Por Wakaskar, Rajesh R., Bathena, Sai Praneeth R., Tallapaka, Shailendra, Ambardekar, Vishakha V., Gautum, Nagsen, Thakare, Rhishikesh N., Simet, Samantha M., Curran, Stephen M., Singh, Rakesh K., Dong, Yuxiang, Vetro, Joseph A.
Publicado no Pharm Res (2014)