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Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti‐tumor activity in vivo

Cytotoxic T cells (CTLs) can eliminate tumor cells through the delivery of lethal hits, but the actual efficiency of this process in the tumor microenvironment is unclear. Here, we visualized the capacity of single CTLs to attack tumor cells in vitro and in vivo using genetically encoded reporters t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EMBO J
मुख्य लेखकों: Khazen, Roxana, Cazaux, Marine, Lemaître, Fabrice, Corre, Beatrice, Garcia, Zacarias, Bousso, Philippe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167356/
https://ncbi.nlm.nih.gov/pubmed/33855732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106658
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